The local supermassive black hole mass density: corrections for dependencies on the Hubble constant

We have investigated past measurements of the local supermassive black hole mass density, correcting for hitherto unknown dependencies on the Hubble constant, which, in some cases, had led to an underestimation of the mass density by factors of ~2. Correcting for this, we note that the majority of past studies yield a local supermassive black hole mas density that is consistent with the range 4.4-5.9 x 10^5 f(H_0) M_Sun / Mpc^3 (when using H_0 = 70 km/s/Mpc). In addition, we address a number of ways in which these past estimates can be further developed. In particular, we tabulate realistic bulge-to-total flux ratios which can be used to estimate the luminosity of bulges and subsequently their central black hole masses.Comment: MNRAS, accepte

Developing a ‘One Health’ Nipah virus vaccine to protect animal and public health

An expanding human population and the concomitant increase in demand for animal protein has led to the use of previously unused habitable land and disruption of ecosystems. Increased human-livestock-wildlife interactions has led to an increase in virus spillover events from wildlife reservoirs, which in turn has elevated the risk of epidemics of new and emerging zoonotic diseases. ‘One Health’ recognises that human, animal, and environmental health are tightly interconnected; an initiative that is righfully gaining more attention in the post-COVID-19 world. Vaccination is a powerful strategy to prevent and control viral outbreaks, as exemplified by the COVID-19 pandemic. Moreover, the vaccination of amplifying intermediate animal hosts provides an effective way to further protect human health. To support efforts to develop vaccines to combat emerging viral zoonoses, we are developing a Nipah virus (NiV) vaccine for use in pigs, which would reduce the risk that NiV poses to the Asian pig industry, livestock keepers and public health. Pig-to-human transmission was responsible for the first and most severe NiV outbreak. This outbreak caused severe and lasting economic costs to the Malaysian pig industry. Despite the threat NiV poses to some of the most pig dense regions of the world, no vaccines are currently available. We have therefore evaluated the immunogenicity of recombinant NiV glycoprotein (G or F) based vaccine candidates delivered as protein subunits or by viral or mRNA vectors in pigs. Three vaccine candidates have been evaluated for efficacy and shown to confer a high degree of protection following a prime-boost regimen. These are now being evaluated under field conditions in Bangladesh. In addition to providing a platform for the further development of a NiV vaccine for pigs, we hope these studies will also benefit ongoing human vaccine development efforts

The Millennium Galaxy Catalogue: The nearby supermassive black hole mass function

We highlight the correlation between a galaxy's supermassive black hole mass and the Sersic-index of the host spheroid or bulge component. From our bulge-disk decompositions of 10 095 galaxies, drawn from the Millennium Galaxy Catalogue, we construct the local (z < 0.18) mass function of supermassive black holes. We compare our results to those of McLure & Dunlop (2004) and conclude that the mass density of supermassive black holes may be marginally higher than previously supposed. This increase is predominantly due to the inclusion of low mass and later-type bulges. More details will be presented in a forthcoming paper.Comment: Contributed article to the Fabulous Destiny of Galaxies meetin

A concise reference to (projected) Sersic R^{1/n} quantities, including Concentration, Profile Slopes, Petrosian indices, and Kron Magnitudes

Given the growing use of Sersic's (1963, 1968) R^{1/n} model for describing the stellar distributions in galaxies, and the lack of any single reference that provides the various associated mathematical expressions, we have endeavoured to compile such a resource here. We present the standard intensity profile, and its various guises such as the luminosity, surface-brightness, and aperture-magnitude profile. Expressions to transform the effective surface brightness into the mean effective and central surface brightness are also given, as is the expression to transform between effective radii and exponential scale-lengths. We additionally provide expressions for deriving the `concentration' of an R^{1/n} profile, and two useful equations for the logarithmic slope of the light-profile are given. Petrosian radii and fluxes are also derived for a range of Sersic profiles and compared with the effective radii and total flux. Similarly, expressions to obtain Kron radii and fluxes are presented as a function of the Sersic index n and the number of effective radii sampled. Illustrative figures are provided throughout. Finally, the core-Sersic model, consisting of an inner power-law and an outer-Sersic function, is presented.Comment: 11 pages. To appear in PAS

Statistics of Lead Changes in Popularity-Driven Systems

We study statistical properties of the highest degree, or most popular, nodes in growing networks. We show that the number of lead changes increases logarithmically with network size N, independent of the details of the growth mechanism. The probability that the first node retains the lead approaches a finite constant for popularity-driven growth, and decays as N^{-phi}(ln N)^{-1/2}, with phi=0.08607..., for growth with no popularity bias.Comment: 4 pages, 4 figures, 2 column revtex format. Minor changes in response to referee comments. For publication in PR

Vaccine Development for Nipah Virus Infection in Pigs

Nipah virus (NiV) causes a severe and often fatal neurological disease in humans. Whilst fruit bats are considered the natural reservoir, NiV also infects pigs and may cause an unapparent or mild disease. Direct pig-to-human transmission was responsible for the first and still most devastating NiV outbreaks in Malaysia and Singapore in 1998–99, with nearly 300 human cases and over 100 fatalities. Pigs can therefore play a key role in the epidemiology of NiV by acting as an “amplifying” host. The outbreak in Singapore ended with the prohibition of pig imports from Malaysia and the Malaysian outbreak was ended by culling 45% of the country's pig population with costs exceeding US$500 million. Despite the importance of NiV as an emerging disease with the potential for pandemic, no vaccines, or therapeutics are currently approved for human or livestock use. In this mini-review, we will discuss current knowledge of NiV infection in pigs; our ongoing work to develop a NiV vaccine for use in pigs; and the pig as a model to support human vaccine development

The supermassive black hole mass - S\'ersic index relations for bulges and elliptical galaxies

Scaling relations between supermassive black hole mass, M_BH, and host galaxy properties are a powerful instrument for studying their coevolution. A complete picture involving all of the black hole scaling relations, in which each relation is consistent with the others, is necessary to fully understand the black hole-galaxy connection. The relation between M_BH and the central light concentration of the surrounding bulge, quantified by the S\'ersic index n, may be one of the simplest and strongest such relations, requiring only uncalibrated galaxy images. We have conducted a census of literature S\'ersic index measurements for a sample of 54 local galaxies with directly measured M_BH values. We find a clear M_BH - n relation, despite an appreciable level of scatter due to the heterogeneity of the data. Given the current M_BH - L_sph and the L_sph - n relations, we have additionally derived the expected M_BH - n relations, which are marginally consistent at the 2 sigma level with the observed relations. Elliptical galaxies and the bulges of disc galaxies are each expected to follow two distinct bent M_BH - n relations due to the S\'ersic/core-S\'ersic divide. For the same central light concentration, we predict that M_BH in the S\'ersic bulges of disc galaxies are an order magnitude higher than in S\'ersic elliptical galaxies if they follow the same M_BH - L_sph relation.Comment: 12 pages, 6 figures, 5 tables, accepted for publication in MNRA

The Millennium Galaxy Catalogue: morphological classification and bimodality in the colour-concentration plane

Using 10 095 galaxies (B < 20 mag) from the Millennium Galaxy Catalogue, we derive B-band luminosity distributions and selected bivariate brightness distributions for the galaxy population. All subdivisions extract highly correlated sub-sets of the galaxy population which consistently point towards two overlapping distributions. A clear bimodality in the observed distribution is seen in both the rest-(u-r) colour and log(n) distributions. The rest-(u-r) colour bimodality becomes more pronounced when using the core colour as opposed to global colour. The two populations are extremely well separated in the colour-log(n) plane. Using our sample of 3 314 (B < 19 mag) eyeball classified galaxies, we show that the bulge-dominated, early-type galaxies populate one peak and the bulge-less, late-type galaxies occupy the second. The early- and mid-type spirals sprawl across and between the peaks. This constitutes extremely strong evidence that the fundamental way to divide the luminous galaxy population is into bulges and discs and that the galaxy bimodality reflects the two component nature of galaxies and not two distinct galaxy classes. We argue that these two-components require two independent formation mechanisms/processes and advocate early bulge formation through initial collapse and ongoing disc formation through splashback, infall and merging/accretion. We calculate the B-band luminosity-densities and stellar-mass densities within each subdivision and estimate that the z ~ 0 stellar mass content in spheroids, bulges and discs is 35 +/- 2 per cent, 18 +/- 7 and 47 +/- 7 per cent respectively. [Abridged]Comment: Accepted for publication in MNRAS, 23 pages, 17 figures. Comments welcome. MGC website is at: http://www.eso.org/~jliske/mgc

The Millennium Galaxy Catalogue: The MbhM_{bh}--LspheroidL_{spheroid} derived supermassive black hole mass function

Supermassive black hole mass estimates are derived for 1743 galaxies from the Millennium Galaxy Catalogue using the recently revised empirical relation between supermassive black hole mass and the luminosity of the host spheroid. The MGC spheroid luminosities are based on $R^{1/n}$-bulge plus exponential-disc decompositions. The majority of black hole masses reside between $10^6 M_{\odot}$ and an upper limit of $2\times10^9 M_{\odot}$. Using previously determined space density weights, we derive the SMBH mass function which we fit with a Schechter-like function. Integrating the black hole mass function over $10^6< M_{bh}/ M_{\odot} < 10^{10}$ gives a supermassive black hole mass density of ($3.8 \pm 0.6) \times 10^5 h^{3}_{70} M_{\odot}$ Mpc$^{-3}$ for early-type galaxies and ($0.96 \pm 0.2) \times10^5 h^{3}_{70} M_{\odot}$ Mpc$^{-3}$ for late-type galaxies. The errors are estimated from Monte Carlo simulations which include the uncertainties in the $M_{bh}$--$L$ relation, the luminosity of the host spheroid and the intrinsic scatter of the $M_{bh}$--$L$ relation. Assuming supermassive black holes form via baryonic accretion we find that ($0.008\pm0.002) h_{70}^{3}$ per cent of the Universe's baryons are currently locked up in supermassive black holes. This result is consistent with our previous estimate based on the $M_{bh}$--$n$ (S{\'e}rsic index) relation.Comment: 10 pages, 6 figures, accepted to MNRA